Announcement PDF RNS Number : 2352J Shield Therapeutics PLC 18 December 2020 Shield Therapeutics plc ("Shield" or the "Group" or the "Company") PDMR Exercise of Share Options London, UK, 18 December 2020: Shield Therapeutics plc (LSE: STX), a commercial stage, pharmaceutical company with a focus on addressing iron deficiency with its lead product Feraccru®/Accrufer® (ferric maltol), announces that it issued and allotted 158,730 new Ordinary Shares of 1.5p each on 18 December 2020 following the exercise of options under the Shield Therapeutics Retention and Performance Share Plan and The Shield Therapeutics plc Long-Term Incentive Plan. Tim Watts, Chief Executive Officer and a PDMR, exercised 100,000 options granted to him on 27 August 2019 at an exercise price of 1.5p each. Mr Watts is retaining the resultant ordinary shares and now holds 648,700 ordinary shares in Shield representing 0.55% of the Company's issued share capital. The 158,730 new Ordinary Shares will be admitted to trading on Aim in accordance with the block listing that the Company applied for on 2 March 2020. Following admission, the Company's issued share capital will comprise 117,505,765 Ordinary Shares and each Ordinary Share carries one vote. There are no Ordinary Shares held in treasury and accordingly, the total number of voting rights is 117,505,765. This figure may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in the Company under the FCA's Disclosure Guidance and Transparency Rules. 1. Details of the Person Discharging Managerial Responsibility ("PDMR")/person closely associated with them ("PCA") a) Name 2. Reason for the notification a) Position/status Chief Executive Officer b) Initial notification/ Initial Notification amendment Tim Watts 3. Details of the Issuer a) Name Shield Therapeutics plc b) LEI code 213800G74QWY15FC3W71 4. Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted a) Description of the financial instrument Identification code Exercise of share options over Ordinary Shares ISIN: GB00BYV81293 b) Nature of the transaction Exercise of awards over Ordinary Shares under the Company's Retention and Performance Share Plan. c) Price(s) and volumes(s) 2020 RPSP Award d) Price (£) Volume 0.015 100,000 Aggregated information - Aggregate volume 100,000 shares in total - Price 1.5p each e) Date of the transaction 18 December 2020 f) Place of the transaction Outside of trading venue For further information please contact: Shield Therapeutics plc Tim Watts, CEO www.shieldtherapeutics.com +44 (0)20 7186 8500 Lucy Huntington-Bailey, Company Secretary and General Counsel Nominated Adviser and Joint Broker Peel Hunt LLP James Steel/Dr Christopher Golden Joint Broker finnCap Ltd Geoff Nash/Matt Radley/Alice Lane Financial PR & IR Advisor Walbrook PR Paul McManus/Lianne Cawthorne +44 (0)19 1511 8500 +44 (0)20 7418 8900 +44 (0)20 7220 0500 +44 (0)20 7933 8780 or shield@walbrookpr.com +44 (0)7980 541 893 / +44 (0)7584 391 303 About Shield Therapeutics plc Shield is a de-risked, specialty pharmaceutical company focused on commercialising its lead product, Feraccru®/Accrufer®, a novel, stable, non-salt based oral therapy for adults with iron deficiency with or without anaemia. Feraccru®/Accrufer® has been approved for use in the United States, European Union, UK and Switzerland and has exclusive IP rights until the mid-2030s. Feraccru is commercialised in the UK and Europe by Norgine B.V. and the Company is currently in the process of selecting a commercialisation partner for the US market. Shield also has an exclusive licence agreement with Beijing Aosaikang Pharmaceutical Co., Ltd., for the development and commercialisation of Feraccru®/Accrufer® in China, Hong Kong, Macau and Taiwan. For more information, please visit www.shieldtherapeutics.com. Follow Shield on Twitter @ShieldTx This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com. RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy. END DSHUWABRROUUAAA